Trop-2 is a transmembrane signal transducer that can induce cancer growth. Using antibody targeting and N-terminal Edman degradation. we show here that Trop-2 undergoes cleavage in the first thyroglobulin domain loop of its extracellular region. between residues R87 and T88. https://foldlyers.shop/product-category/firewire/
Trop-2 cleavage by ADAM10 is an activator switch for cancer growth and metastasis
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