The evolution of antimicrobial resistance can be strongly affected by variations of antimicrobial concentration. Here. we study the impact of periodic alternations of absence and presence of antimicrobial on resistance evolution in a microbial population. using a stochastic model that includes variations of both population composition and size. https://safeersappliancers.shop/product-category/siemens-gs29nvw3pg-161cm-tall-freezer/