Abstract Endosomal nucleic acid sensing by Toll-like receptors (TLRs) is central to antimicrobial immunity and several autoimmune conditions such as systemic lupus erythematosus (SLE). The innate immune adaptor TASL mediates. via the interaction with SLC15A4. the activation of IRF5 downstream of human TLR7. https://atome3des.shop/product-category/accessoires-polymaker/