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The chromosomal association of the Smc5/6 complex depends on cohesion and predicts the level of sister chromatid entanglement.

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The cohesin complex. which is essential for sister chromatid cohesion and chromosome segregation. also inhibits resolution of sister chromatid intertwinings (SCIs) by the topoisomerase Top2. The cohesin-related Smc5/6 complex (Smc5/6) instead accumulates on chromosomes after Top2 inactivation. https://allfixelectricales.shop/product-category/dishwasher-basket-wheel-axle/
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