[english] Nail-patella syndrome (NPS) is a pleiotropic autosomal-dominant disorder due to mutations in the gene LMX1B. It has traditionally been characterized by a tetrad of dermatologic and musculoskeletal abnormalities. However. one of the most serious manifestations of NPS is kidney disease. https://www.infonoticiasgandia.com/product-category/coffee-machine-parts/